A retrospective study of 129 patients with plasma cell balanitis
نویسندگان
چکیده
Background Plasma cell balanitis (PCB) is a chronic inflammatory dermatosis of the glans penis and prepuce, typically presenting as discrete shiny bright red plaques. Research on PCB scarce, with case reports small series. The aetiology, incidence prevalence remain unclear. Circumcision considered treatment choice. Topical treatments such topical corticosteroids, calcineurin inhibitors, fucidic acid imiquimod have been widely used, but they lack evidence efficacy. Objectives objective this study was to investigate clinical profiles, methods outcomes patients in relatively large cohort. Methods We concluded retrospective 129 diagnosis between 1 January 2003 31 December 2018 at Tampere University Hospital (TAYS) dermatology department. Results majority were treated only, while (24%) eventually underwent circumcision. most used effective tacrolimus (0.03% or 0.1%) clobetasol propionate. Those circumcision had shorter follow-up time (median 8 months vs. 47 months, p = 0.002) more likely reach remission (46% 16%, compared those only treatments. Patients severe symptoms often several undergo circumcision, ultimately remission. longer among histopathologic than 16 6 0.01). Conclusions are rarely curative, them corticosteroids show strongest rate significantly better circumcised, it be already an early stage. Further studies needed find best care management for PCB.
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ژورنال
عنوان ژورنال: JEADV Clinical Practice
سال: 2023
ISSN: ['2768-6566']
DOI: https://doi.org/10.1002/jvc2.141